Forecast horizon — calibration-scored at resolution.
By 2028, stent retrievers will remain first-line device class, with next-gen aspiration-plus-stent hybrids not yet unseating them in RCTs.
TL;DR · AI-generated
In patients receiving intravenous t-PA for acute ischemic stroke, thrombectomy with the use of a stent retriever within 6 hours after onset improved functional outcomes at 90 days.
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Evidence stream
2 events · 1 snapshot
posterior drift
71% → 71% (0pp · 1 point)
Registry data
Apr 18, 2026
Peer-reviewed paper
Apr 18, 2026
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Source publication
Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke
Jeffrey L. Saver et al. · New England Journal of Medicine · 2015
· openalex W2037399775 · s2 e406b8b3
Semantically related
Nearest claims in the expert-corpus vector space. Ordered by cosine distance — lower is closer.
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Retrievable stent retrievers are the predominant device used in intraarterial stroke treatment, employed in 81.5% of patients assigned to the intervention arm in this trial.
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By 2028, CT-perfusion will be standard at the majority of thrombectomy-capable centers, matching the EXTEND-IA selection criteria.
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By 2028, flow-diverter use will extend to posterior circulation aneurysms with safety non-inferior to anterior-circulation benchmarks.
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By 2028, late-window thrombectomy (6–24h) will be explicitly endorsed by AHA/ASA guidelines as standard-of-care in qualifying LVO patients across at least 80% of US comprehensive stroke centers.
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The SWIFT PRIME trial's stated primary conclusion — Stent-retriever thrombectomy plus tPA is superior to tPA alone for proximal anterior-circulation stroke. — replicates in independent cohorts.
0.2099
By 2028, imaging-based (CTP/MR) selection for late-window thrombectomy will be reimbursed by CMS without pre-authorization.