Built on public scientific infrastructure
MAYO CLINIC
DUKE
STANFORD
MIT
JOHNS HOPKINS
NIH
UCSF
MGH
Sciync is an independent platform. Institution names above reference the research networks our contributors publish within; they do not imply endorsement.
01 — Architecture
Three pillars, one primitive.
Sciync is one expert-weighted consensus engine, applied across three temporal layers of scientific truth. The primitive is a claim — validated by humans you can verify.
Noosphere
Retrospective · GitHub for science
Collaborative authoring, version-controlled noemes, reproducible methods. Every paper a mergeable artifact; every dataset a cited commit.
Consensus
Prospective · Trust-weighted aggregates
Reputation-weighted consensus across historical, current, and future noemes. ORCID-verified experts weighted; anyone may participate. Equipoise-gated for actively enrolling trials.
Alignment
Truth Silos™ · Ground truth for the AI era
Expert-validated noeme store that grounds LLMs in peer-reviewed medicine. Retrieval-augmented generation with provenance back to the human who validated it.
Platform
One primitive. Three surfaces.
A single claim primitive powers every layer. Each surface reads and writes the same underlying expert consensus.
02 — Comparison
Endpoint Arena vs Sciync.
Endpoint Arena asked an important question. We think the answer needs different machinery — one where humans who publish the science are the signal, and where no patient outcome is a tradable position.
Stakes
Money on patient outcomes
Reputation on knowledge claims
Participants
9 AI models (no humans in the loop)
ORCID-verified experts + AI support
Temporal scope
Future only
Past + present + future
Domain
Clinical trial outcomes
Scientific knowledge, broadly
Weighting
Dollar-weighted
Reputation × expertise × calibration
Ethics
Patient-outcome-as-instrument
Halal by design, equipoise-gated
Securities
Potential CFTC / securities exposure
None (no tradable positions)
Product
AI leaderboard
Information product for enterprise
Both ask "will drug X succeed?" We answer it differently.
Integrations
Integrated with the sources scientists already trust.
Noemes, citations, and expert identity are grounded in public scientific infrastructure. AI providers are pluggable, not exclusive.
Scientific data sources
PubMed
ClinicalTrials.gov
Crossref
ORCID
OpenAlex
FDA openFDA
AI providers
Claude
Gemini
Voyage AI
OpenAI
Groq
04 — Join
Join the waitlist.
30+ Founding Expert slots open. ORCID-verified experts get priority.
05 — Principles
Ethics isn't a section. It's the substrate.
Three of the hard lines we hold. The full list — ORCID verification, conflicts of interest, halal-by-design — lives on our principles page.
No money on patient outcomes — ever.
You will never be able to place a financial bet on whether a trial helps or harms a patient. Reputation is the only stake.
Reputation is non-transferable.
You cannot buy, sell, or gift reputation. It accrues from calibrated, expert judgement and nothing else.
Active trials are equipoise-gated.
While a trial is enrolling, predictions are withheld from public view to protect clinical equipoise and enrollment integrity.