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Noeme · w4h7g312

Forecast horizon — calibration-scored at resolution.

Durvalumab consolidation after chemoradiotherapy will demonstrate a statistically significant overall survival benefit in the final analysis of the PACIFIC trial in stage III unresectable NSCLC.

TL;DR · AI-generated

tldr@v2.0.0
semanticscholar.org

Progression‐free survival was significantly longer with durvalumab than with placebo, and safety was similar between the groups, and the secondary end points also favored durvalsumab.

Author-implied confidence

82%

Current probability

92%

Status

DRAFT

Your probability this resolves TRUE

Consensus 92%

0% (impossible)

50%

100% (certain)

25
50
75

Proper-scoring-rule preview

If TRUE: Brier 0.250 · log 0.69 · +8 rep
If FALSE: Brier 0.250 · log 0.69 · -1 rep
Kelly 25.0% ≈ 250 rep
vs. consensus: 0.88 bits

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Evidence stream

1 event · 1 snapshot

posterior drift

92% → 92% (0pp · 1 point)

posterior drift: 92% → 92%
supports

Peer-reviewed paper

PMID 28885881

Apr 18, 2026

+10pp

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Source publication

Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer.

4.5k citations · S2 2.6k
102 influential
FWCI 316.4 · Landmark
OA · bronze
30 authors · 83% ORCID

· openalex W2753065806 · s2 bc101251