All noemes
Trial · NCT01492725

Noeme · p1jawh1b

Active replication — ongoing trial, registry, or meta-analysis.

Recent follow-up analyses of EXTEND-IA are confirming the original effect size in real-world data.

TL;DR · AI-generated

tldr@v2.0.0
semanticscholar.org

In patients with ischemic stroke with a proximal cerebral arterial occlusion and salvageable tissue on CT perfusion imaging, early thrombectomy with the Solitaire FR stent retriever, as compared with alteplase alone, improved reperfusion, early neurologic recovery, and functional outcome.

Your position — does this noeme still stand given current evidence?

0% (impossible)

50%

100% (certain)

25
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75

Proper-scoring-rule preview

If TRUE: Brier 0.250 · log 0.69 · +8 rep
If FALSE: Brier 0.250 · log 0.69 · -1 rep
Kelly 25.0% ≈ 250 rep

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Evidence stream

2 events · 1 snapshot

posterior drift

71% → 71% (0pp · 1 point)

posterior drift: 71% → 71%
neutral

Registry data

NCT01492725

Apr 18, 2026

supports

Peer-reviewed paper

+21pp

Expert reactions · 0

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Source publication

Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection

Bruce C.V. Campbell et al. · New England Journal of Medicine · 2015

5.8k citations
153 influential
FWCI 482.8 · Landmark
OA · bronze
36 authors · 89% ORCID

· openalex W2119542322 · s2 958d215d