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CLARITY-AD (lecanemab)

Neurology
Phase III
Active
Equipoise gate

CLARITY-AD (lecanemab) · 2023 · New England Journal of Medicine

Lecanemab in Early Alzheimer’s Disease

Lecanemab slows cognitive decline in early Alzheimer disease with amyloid confirmation, with a non-trivial ARIA safety signal.

Source publication

Lecanemab in Early Alzheimer’s Disease

Christopher H. van Dyck et al. · New England Journal of Medicine · 2023

Sponsor

Eisai Inc.

Principal investigator

Population

Early Alzheimer's Disease; n=1906

Primary endpoint

Core Study: Change from Baseline in the CDR-SB at 18 Months

Methodology notes

Full methodology is under curation. This project aggregates 3 seeded claims across three temporal layers. The replication spec, pre-registered analysis, and version history will appear here as the project matures.

Funding progress

$2.0M / $3.5M

56%

Funding displayed here is indicative of collaborator interest. Sciync does not broker money, grants, or securities.

Temporal layers
Historical

Published findings under validation

1

Current

Active replication in progress

1

Future

Forecast horizons pending resolution

1