All noemes

Noeme · pty51zzd

Published finding — does the expert body still believe it?

The absolute cardiovascular benefit of alirocumab over placebo is greater in post-ACS patients with a baseline LDL cholesterol of 100 mg/dL or higher compared to those with lower baseline LDL levels.

TL;DR · AI-generated

tldr@v2.0.0
semanticscholar.org

Among patients who had a previous acute coronary syndrome and who were receiving high‐intensity statin therapy, the risk of recurrent ischemic cardiovascular events was lower among those who received alirocumab than amongThose who received placebo.

Author-implied confidence

82%

Status

DRAFT

Your position — does this noeme still stand given current evidence?

Consensus 82%

0% (impossible)

50%

100% (certain)

25
50
75

Proper-scoring-rule preview

If TRUE: Brier 0.250 · log 0.69 · +8 rep
If FALSE: Brier 0.250 · log 0.69 · -1 rep
Kelly 25.0% ≈ 250 rep
vs. consensus: 0.38 bits

Your position is kept on this device until you sign in.

Evidence stream

1 event · 1 snapshot

posterior drift

92% → 92% (0pp · 1 point)

posterior drift: 92% → 92%
supports

Peer-reviewed paper

PMID 30403574

Apr 18, 2026

+10pp

Expert reactions · 0

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Source publication

Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome.

3.4k citations · S2 2.6k
124 influential
FWCI 334.0 · Landmark
OA · bronze
22 authors · 64% ORCID

· openalex W2899997727 · s2 3bd18f4d