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Scientific Factoids

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116 factoids

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Vascular Neurology

Impact 60

Human

Pending

The MONALEESA-2 trial's stated primary conclusion — Adding ribociclib to letrozole improves progression-free survival in HR+/HER2− advanced breast cancer. — replicates in independent cohorts.

oncology

78%

Accuracy

95%

Confidence

77%

Established

Posted 19/03/26 · Updated 21/04/26

Clinical Neurophysiology

Impact 60

Human

Pending

Pembrolizumab (10 mg/kg every 2 weeks) improves 12-month overall survival to 74.1% versus 58.2% for ipilimumab (HR 0.63, P=0.0005) in patients with advanced melanoma.

oncology

pharmacology

83%

Accuracy

67%

Confidence

60%

Established

Posted 22/01/26 · Updated 21/04/26

Neuroradiology

Impact 60

Verified

Recent follow-up analyses of CLARITY-AD (lecanemab) are confirming the original effect size in real-world data.

neurology

91%

Accuracy

65%

Confidence

74%

Established

Posted 20/04/26 · Updated 21/04/26

Cardiology

Impact 61

Human

Pending

Recent follow-up analyses of EARLYSTIM are confirming the original effect size in real-world data.

neurology

73%

Accuracy

82%

Confidence

84%

Established

Posted 28/03/26 · Updated 21/04/26

Stroke Neurology

Impact 79

Human

Pending

The HGB-206 (lovo-cel) trial's stated primary conclusion — Lentiviral β-globin gene therapy reduces or eliminates VOC events in severe sickle cell disease. — replicates in independent cohorts.

gene-therapy

80%

Accuracy

66%

Confidence

82%

Established

Posted 25/03/26 · Updated 20/04/26

Neurointerventional

Impact 75

Human

Pending

The MR CLEAN trial's stated primary conclusion — Endovascular thrombectomy within 6h improves functional outcome in proximal anterior circulation stroke. — replicates in independent cohorts.

neurointerventional

75%

Accuracy

85%

Confidence

64%

Established

Posted 31/12/25 · Updated 20/04/26

Cardiology

Impact 61

Human

Pending

The EMBOLISE trial's stated primary conclusion — MMA embolization as an adjunct to surgical evacuation lowers recurrence for symptomatic chronic subdural hematoma. — replicates in independent cohorts.

neurointerventional

73%

Accuracy

64%

Confidence

69%

Established

Posted 05/01/26 · Updated 20/04/26

Vascular Neurology

Impact 63

Verified

Recent follow-up analyses of KEYNOTE-522 are confirming the original effect size in real-world data.

oncology

87%

Accuracy

91%

Confidence

90%

Established

Posted 11/04/26 · Updated 20/04/26

Neurointerventional

Impact 93

Verified

Recent follow-up analyses of SWIFT PRIME are confirming the original effect size in real-world data.

neurointerventional

92%

Accuracy

74%

Confidence

84%

Established

Posted 18/04/26 · Updated 19/04/26

Interventional Radiology

Impact 70

Human

Pending

Recent follow-up analyses of EMBOLISE are confirming the original effect size in real-world data.

neurointerventional

75%

Accuracy

82%

Confidence

69%

Established

Posted 06/01/26 · Updated 19/04/26